Identification of a novel gene encoding an insulin-responsive glucose transporter protein

  title={Identification of a novel gene encoding an insulin-responsive glucose transporter protein},
  author={M. Birnbaum},
  • M. Birnbaum
  • Published 1989
  • Biology, Medicine
  • Cell
  • Insulin, rapidly and independently of new protein synthesis, stimulates glucose transport in sensitive target tissues. A cDNA has been cloned from a skeletal muscle library that encodes a novel glucose transporter protein exhibiting the following properties of an insulin-regulated hexose carrier protein: it is expressed exclusively in adipose tissue, skeletal muscle and heart, the principal organs with insulin-responsive glucose transport; RNA transcribed from the muscle cDNA, when expressed in… CONTINUE READING
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