Identification of a novel CD160+ CD4+ T-lymphocyte subset in the skin: a possible role for CD160 in skin inflammation.

@article{Abecassis2007IdentificationOA,
  title={Identification of a novel CD160+ CD4+ T-lymphocyte subset in the skin: a possible role for CD160 in skin inflammation.},
  author={Sofia Abecassis and J{\'e}r{\^o}me Giustiniani and N Meyer and Val{\'e}rie Schiavon and N Ortonne and Jos{\'e} Antonio Campillo and Martine Bagot and Armand Bensussan},
  journal={The Journal of investigative dermatology},
  year={2007},
  volume={127 5},
  pages={
          1161-6
        }
}
CD160 is a glycosylphosphatidylinositol-anchored cell surface molecule expressed by human circulating cytotoxic lymphocytes that correspond to the majority of natural killer cell (NK) expressing CD56(dim), TCRgammadelta lymphocytes, and to a minor CD8 T-cell subset. CD160 engagement by major histocompatibility complex class I molecules triggers by itself both cytotoxic function and cytokine production in NK lymphocytes, whereas it provides co-activating signals to TCR-induced proliferation in T… CONTINUE READING

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