Identification of a new member of the CD20/FcepsilonRIbeta family overexpressed in tolerated allografts.

@article{Louvet2005IdentificationOA,
  title={Identification of a new member of the CD20/FcepsilonRIbeta family overexpressed in tolerated allografts.},
  author={C{\'e}dric Louvet and Elise Chiffoleau and Mich{\`e}le Heslan and Laurent Tesson and Jean-Marie Heslan and R{\'e}gis Brion and Ga{\"e}lle B{\'e}riou and Carole Guillonneau and Jamal Khalife and Ignacio Anegon and Maria-Cristina Cuturi},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2005},
  volume={5 9},
  pages={2143-53}
}
We identified a novel rat gene specifically overexpressed in tolerated heart allografts in a model of tolerance induced by donor-specific blood transfusion (DST). We named this gene TORID, for tolerance-related and induced transcript. We show that TORID expression can be attributed to non-T cells infiltrating tolerated grafts. Interestingly, TORID overexpression was also observed in long-term grafts from a different model of tolerance in which chronic rejection does not occur. Comparison of the… CONTINUE READING
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