Identification of a new impurity in lisinopril.

@article{Shinde2007IdentificationOA,
  title={Identification of a new impurity in lisinopril.},
  author={Vikas R Shinde and Anurag Trivedi and Preeti Upadhayay and Nalin Lochan Gupta and D G Kanase and Rajeev C. Chikate},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={2007},
  volume={43 1},
  pages={381-6}
}
LC-UV scan of lisinopril revealed the presence of an unknown impurity (approximately 0.14%) at a relative retention time of 3.26 employing phosphate buffer-acetonitrile as binary gradient system while LC-MS analysis with binary gradient system comprising of a ammonia-ammonium acetate buffer (pH 5.0) and acetonitrile indicated it to be C31H41N3O7. The… CONTINUE READING