Identification of a new commonly deleted region within a 2-cM interval of chromosome 11p11 in breast cancers.

@article{Nakata1998IdentificationOA,
  title={Identification of a new commonly deleted region within a 2-cM interval of chromosome 11p11 in breast cancers.},
  author={Takao Nakata and Masataka Yoshimoto and Fujio Kasumi and Futoshi Akiyama and Goi Sakamoto and Yoko Nakamura and Mitsuru Emi},
  journal={European journal of cancer},
  year={1998},
  volume={34 3},
  pages={417-21}
}
Allelic loss has been observed on the short arm of chromosome 11 in a variety of human cancers. We have examined 184 breast cancers for allelic loss anywhere in chromosome 11p, using 15 well-spaced microsatellite markers. Allelic loss was observed in 86 cases (47%) and a new commonly deleted region 2-cM in length was identified at 11p11 between loci D11S986… CONTINUE READING