Identification of a new C-type lectin, TES-70, secreted by infective larvae of Toxocara canis, which binds to host ligands.

@article{Loukas2000IdentificationOA,
  title={Identification of a new C-type lectin, TES-70, secreted by infective larvae of Toxocara canis, which binds to host ligands.},
  author={Alex Loukas and Andrew Doedens and Martin Hintz and Rick M. Maizels},
  journal={Parasitology},
  year={2000},
  volume={121 Pt 5},
  pages={545-54}
}
Infective larvae of the dog roundworm Toxocara canis survive in the tissues of their hosts for extended periods in a state of developmental arrest, successfully evading immune destruction. This survival strategy is thought to be mediated by T. canis excretory/secretory (TES) products which downregulate or divert the immune response. We purified one of the major TES products, TES-70 and gained amino acid sequence from 4 tryptic peptides. These peptides were matched to a predicted protein from a… CONTINUE READING

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