Identification of a neuronal cell surface molecule, plexin, in mice.

  title={Identification of a neuronal cell surface molecule, plexin, in mice.},
  author={Tadamitsu Kameyama and Yuko Murakami and Fumikazu Suto and Atsushi Kawakami and Shingo Takagi and Taku Hirata and Hajime Fujisawa},
  journal={Biochemical and biophysical research communications},
  volume={226 2},
We searched for mouse homologues of the cell adhesion protein plexin which was originally found in Xenopus, and obtained a cDNA encoding a plexin-like protein. We referred to this protein as mouse plexin 1. The overall amino acid identity between mouse plexin 1 and Xenopus plexin was 84%. As in the Xenopus plexin, the extracellular segment of mouse plexin 1 protein possessed three cysteine-rich domains which showed significant homology with the cysteine-rich domain of the c-Met proto-oncogene… CONTINUE READING

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