Identification of a mouse cytoskeleton-associated protein, CKAP2, with microtubule-stabilizing properties.

@article{Jin2004IdentificationOA,
  title={Identification of a mouse cytoskeleton-associated protein, CKAP2, with microtubule-stabilizing properties.},
  author={Yi Feng Jin and Yoshiki Murakumo and Kaoru Ueno and Mizuo Hashimoto and Tsuyoshi Ichihara-shi Watanabe and Yoshie Shimoyama and Masatoshi Ichihara and Masahide Takahashi},
  journal={Cancer science},
  year={2004},
  volume={95 10},
  pages={
          815-21
        }
}
Microtubule dynamics is an important factor in cell proliferation and one of the main targets of cancer chemotherapy. Since microtubule-associated proteins (MAPs) are known to influence microtubule stability, study of MAPs may contribute both to knowledge of cancer cell biology and to the production of new anti-cancer drugs. In this study, we identified a new mouse gene which is a homolog of human cytoskeleton-associated protein, CKAP2 gene, by differential display analysis. The level of… CONTINUE READING
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