Identification of a mouse TBP-like protein (TLP) distantly related to the drosophila TBP-related factor.

  title={Identification of a mouse TBP-like protein (TLP) distantly related to the drosophila TBP-related factor.},
  author={Tetsu Ohbayashi and Yasutaka Makino and Tomonari Tamura},
  journal={Nucleic acids research},
  volume={27 3},
TATA-binding protein (TBP) is an essential factor for eukaryotic transcription. In this study, we demonstrated a mouse cDNA encoding a 21 kDa TBP-like protein (TLP). The TLP ORF, carrying 186 amino acids, covered the entire 180 amino acids of the C-terminal conserved domain of mouse TBP with 39% identity and 76% similarity. Northern blot analysis demonstrated that TLP mRNAs were expressed in various mammalian tissues ubiquitously and that their distribution pattern was analogous to that of TBP… CONTINUE READING


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