Identification of a matrix-associated region 5' of an immunoglobulin heavy chain variable region gene.

@article{Webb1991IdentificationOA,
  title={Identification of a matrix-associated region 5' of an immunoglobulin heavy chain variable region gene.},
  author={Carol F Webb and Chandrima Das and K L Eneff and Philip W. Tucker},
  journal={Molecular and cellular biology},
  year={1991},
  volume={11 10},
  pages={5206-11}
}
In the accompanying report (C. F. Webb, C. Das, S. Eaton, K. Calame, and P. Tucker, Mol. Cell. Biol. 11:5197-5205, 1991), we characterize B-cell-specific protein-DNA interactions at -500 and -200 bp upstream of the mu immunoglobulin heavy chain promoter whose abundances were increased by interleukin-5 plus antigen. Because of the high A + T/G + C ratio of these sequences and the consistent findings by others that enhancer- and promoterlike regions are often located near matrix-associated… CONTINUE READING
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