Identification of a major antigenic epitope on CNBr-fragment 11 of type II collagen recognized by murine autoreactive B cells.

Abstract

Immunization of certain strains of mice with native type II collagen (CII) induces both development of arthritis and an antibody response to autologous CII. The autoantibody response in a high-responder strain, the DBA/1 mouse, has been described earlier, and a number of monoclonal antibodies have been characterized for arthritogenicity and autoreactive… (More)

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Cite this paper

@article{Burkhardt1991IdentificationOA, title={Identification of a major antigenic epitope on CNBr-fragment 11 of type II collagen recognized by murine autoreactive B cells.}, author={H. Burkhardt and Richard Holmdahl and Rainer Deutzmann and H. G. Wiedemann and Helga von der Mark and Steven D Goodman and Klaus von der Mark}, journal={European journal of immunology}, year={1991}, volume={21 1}, pages={49-54} }