Identification of a hypervariable region in the long terminal repeat of equine infectious anemia virus.

@article{Carpenter1991IdentificationOA,
  title={Identification of a hypervariable region in the long terminal repeat of equine infectious anemia virus.},
  author={Susan Carpenter and Soren Alexandersen and Michael J. Long and Sharon Perryman and Bruce W. Chesebro},
  journal={Journal of virology},
  year={1991},
  volume={65 3},
  pages={
          1605-10
        }
}
An avirulent, field-derived isolate of equine infectious anemia virus (EIAV), designated MA-1, was molecularly cloned, and the complete nucleotide sequence was determined for the 3' half of the viral genome. Comparisons between MA-1 and the prototype Wyoming strain of EIAV identified a 66-nucleotide stretch between CAAT (-91) and TATAA (-25) in the U3 region of the long terminal repeat, where sequence divergence was as high as 39.3%. The polymerase chain reaction was used to amplify and clone… CONTINUE READING

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