Identification of a growth arrest specific (gas 5) gene by differential display as a candidate gene for determining susceptibility to hyperthermia-induced exencephaly in mice.

@article{Vacha1997IdentificationOA,
  title={Identification of a growth arrest specific (gas 5) gene by differential display as a candidate gene for determining susceptibility to hyperthermia-induced exencephaly in mice.},
  author={Scott J Vacha and Gregory D. Bennett and Scott A. Mackler and M J Koebbe and Richard H. Finnell},
  journal={Developmental genetics},
  year={1997},
  volume={21 3},
  pages={212-22}
}
Neural tube defects (NTDs) are among the most common congenital malformations, affecting approximately 1 per 1,000 liveborn infants in the United States [Nakano, 1973; Richards et al., 1972]. Maternal exposure to hyperthermia, either through recreational sources or due to an infectious agent, is thought to account for approximately 10% of observed NTD cases. The specific genes conferring susceptibility or resistance to hyperthermia-induced NTDs have not been identified. This study used… CONTINUE READING