Identification of a genetic marker for isometamidium chloride resistance in Trypanosoma congolense.

@article{Delespaux2005IdentificationOA,
  title={Identification of a genetic marker for isometamidium chloride resistance in Trypanosoma congolense.},
  author={Vincent Delespaux and D. M. Geysen and Phelix A. O. Majiwa and Stanny Geerts},
  journal={International journal for parasitology},
  year={2005},
  volume={35 2},
  pages={235-43}
}
Isometamidium chloride has remained a very important prophylactic and therapeutic drug against trypanosomosis in cattle since its introduction into the market in the 1950s with, unfortunately, a concomitant development of resistance in trypanosomosis endemic areas. Amplified Fragment Length Polymorphism (AFLP) was used to compare two isogenic clones of Trypanosoma congolense. The parent clone, sensitive to isometamidium, has a CD50 (the curative dose that gives complete cure in 50% of the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…