Identification of a genetic determinant responsible for host specificity in Streptococcus thermophilus bacteriophages.

@article{Duplessis2001IdentificationOA,
  title={Identification of a genetic determinant responsible for host specificity in Streptococcus thermophilus bacteriophages.},
  author={Martin Duplessis and Sylvain Moineau},
  journal={Molecular microbiology},
  year={2001},
  volume={41 2},
  pages={
          325-36
        }
}
Phage-host interactions remain poorly understood in lactic acid bacteria and essentially in all Gram-positive bacteria. The aim of this study was to identify the phage genetic determinant (anti-receptor) involved in the recognition of Streptococcus thermophilus hosts. The complete genomic sequence of the lytic S. thermophilus phage DT1 was determined previously, and bioinformatic analysis indicated that orf18 might be the anti-receptor gene. The orf18 of six additional S. thermophilus phages… CONTINUE READING

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