Identification of a gene signature in cell cycle pathway for breast cancer prognosis using gene expression profiling data

@article{Liu2008IdentificationOA,
  title={Identification of a gene signature in cell cycle pathway for breast cancer prognosis using gene expression profiling data},
  author={Jiangang Liu and Andrew Campen and Shuguang Huang and Sheng-bin Peng and Xiang S. Ye and Mathew J. Palakal and A. Keith Dunker and Yuni Xia and Shuyu D. Li},
  journal={BMC Medical Genomics},
  year={2008},
  volume={1},
  pages={39 - 39}
}
Numerous studies have used microarrays to identify gene signatures for predicting cancer patient clinical outcome and responses to chemotherapy. However, the potential impact of gene expression profiling in cancer diagnosis, prognosis and development of personalized treatment may not be fully exploited due to the lack of consensus gene signatures and poor understanding of the underlying molecular mechanisms. We developed a novel approach to derive gene signatures for breast cancer prognosis in… CONTINUE READING
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