Identification of a gene involved in the biosynthesis pathway of the terminal sugar of the archaellin N-linked tetrasaccharide in Methanococcus maripaludis

@article{Ding2015IdentificationOA,
  title={Identification of a gene involved in the biosynthesis pathway of the terminal sugar of the archaellin N-linked tetrasaccharide in Methanococcus maripaludis},
  author={Y. Y. Ding and Gareth M. Jones and Cedric Brimacombe and Kaoru Uchida and Shin-ichi Aizawa and Susan M Logan and John F Kelly and Ken F Jarrell},
  journal={Antonie van Leeuwenhoek},
  year={2015},
  volume={109},
  pages={131-148}
}
In Methanococcus maripaludis, the three archaellins which comprise the archaellum are modified at multiple sites with an N-linked tetrasaccharide with the structure of Sug-4-β-ManNAc3NAmA6Thr-4-β-GlcNAc3NAcA-3-β-GalNAc, where Sug is a unique sugar (5S)-2-acetamido-2,4-dideoxy-5-O-methyl-l-erythro-hexos-5-ulo-1,5-pyranose, so far found exclusively in this species. In this study, a six-gene cluster mmp1089–1094, neighboring one of the genomic regions already known to contain genes involved with… CONTINUE READING
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