Identification of a functional Na+/Mg2+ exchanger in human trophoblast cells.

  title={Identification of a functional Na+/Mg2+ exchanger in human trophoblast cells.},
  author={Paul R Standley and Cynthia A Standley},
  journal={American journal of hypertension},
  volume={15 6},
BACKGROUND Ionized magnesium levels are elevated in fetal blood compared with maternal blood, suggesting that the placenta may possess an active transport mechanism for magnesium. In the present study, we sought to determine the existence of an active transport mechanism for magnesium in the placenta using cultured trophoblast cells. METHODS Using choriocarcinoma cells as a model system, we attempted to demonstrate the presence of a functional Na+/Mg2+ exchanger. Human choriocarcinoma JEG-3… CONTINUE READING


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