Identification of a fmtA-like gene that has similarity to other PBPs and beta-lactamases in Staphylococcus aureus.

@article{Komatsuzawa2000IdentificationOA,
  title={Identification of a fmtA-like gene that has similarity to other PBPs and beta-lactamases in Staphylococcus aureus.},
  author={Hitoshi Komatsuzawa and Gil H. Choi and Tamaki Fujiwara and Y Huang and Kouji Ohta and Motoyuki Sugai and Hidekazu Suginaka},
  journal={FEMS microbiology letters},
  year={2000},
  volume={188 1},
  pages={
          35-9
        }
}
We identified a gene from Staphylococcus aureus, flp (fmtA-like protein), encoding a protein of 489 amino acid residues with a molecular mass of 56.4 kDa. The deduced amino acid sequence shows similarity to previously characterized penicillin binding proteins (PBPs) and FmtA of S. aureus (one of the factors which affect methicillin resistance). FLP protein has three motifs, which are conserved in PBPs and beta-lactamases, suggesting that it might be associated with cell wall synthesis… CONTINUE READING