Identification of a flavonol 7-O-rhamnosyltransferase gene determining flavonoid pattern in Arabidopsis by transcriptome coexpression analysis and reverse genetics.

@article{YonekuraSakakibara2007IdentificationOA,
  title={Identification of a flavonol 7-O-rhamnosyltransferase gene determining flavonoid pattern in Arabidopsis by transcriptome coexpression analysis and reverse genetics.},
  author={Keiko Yonekura-Sakakibara and Takayuki Tohge and Rie Niida and Kazuki Saito},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 20},
  pages={14932-41}
}
Glycosylation plays a major role in the remarkable chemical diversity of flavonoids in plants including Arabidopsis thaliana. The wide diversity encoded by the large family-1 glycosyltransferase (UGT) gene family makes it difficult to determine the biochemical function of each gene solely from its primary sequence. Here we used transcriptome coexpression analysis combined with a reverse genetics approach to identify a gene that is prominent in determining the flavonoid composition of… CONTINUE READING
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