Identification of a dominant CD4 T cell epitope in the membrane lipoprotein Tul4 from Francisella tularensis LVS.

@article{Valentino2009IdentificationOA,
  title={Identification of a dominant CD4 T cell epitope in the membrane lipoprotein Tul4 from Francisella tularensis LVS.},
  author={Michael D. Valentino and Lucinda L. Hensley and Denise Skrombolas and Pamela L McPherson and Matthew D. Woolard and Thomas H Kawula and Jeffrey A Frelinger and John G. Frelinger},
  journal={Molecular immunology},
  year={2009},
  volume={46 8-9},
  pages={
          1830-8
        }
}
Francisella tularensis is a gram-negative intracellular bacterium that is the causative agent of tularemia. Small mammals such as rodents and rabbits, as well as some biting arthropods, serve as the main vectors for environmental reservoirs of F. tularensis. The low infectious dose, ability to aerosolize the organism, and the possibility of generating antibiotic resistant strains make F. tularensis a prime organism for use in bioterrorism. As a result, some strains of F. tularensis have been… CONTINUE READING
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