Identification of a calicivirus isolate of unknown origin.

  title={Identification of a calicivirus isolate of unknown origin.},
  author={Angelika Oehmig and Mathias Buettner and Frank Weiland and William Werz and Klaus Bergemann and Eberhard Pfaff},
  journal={The Journal of general virology},
  volume={84 Pt 10},
Chinese hamster ovary (CHO) cells manifesting striking cytopathogenic changes in culture were investigated to determine the causative agent. Electron microscopic analyses revealed viral particles of about 40 nm in diameter, displaying typical calicivirus morphology. To date, this virus, designated isolate 2117, exclusively replicates in CHO cells, achieving only moderate titres. After cloning, the coding region of 7928 nucleotides, the 3' non-coding region and the poly(A) tail were sequenced… CONTINUE READING
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  • 1978
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