Identification of a cDNA clone that contains the complete coding sequence for a 140-kD rat NCAM polypeptide

@article{Small1987IdentificationOA,
  title={Identification of a cDNA clone that contains the complete coding sequence for a 140-kD rat NCAM polypeptide},
  author={S J Small and Gary E. Shull and M J Santoni and Richard Akeson},
  journal={The Journal of Cell Biology},
  year={1987},
  volume={105},
  pages={2335 - 2345}
}
Neural cell adhesion molecules (NCAMs) are cell surface glycoproteins that appear to mediate cell-cell adhesion. In vertebrates NCAMs exist in at least three different polypeptide forms of apparent molecular masses 180, 140, and 120 kD. The 180- and 140-kD forms span the plasma membrane whereas the 120-kD form lacks a transmembrane region. In this study, we report the isolation of NCAM clones from an adult rat brain cDNA library. Sequence analysis indicated that the longest isolate, pR18… CONTINUE READING