Identification of a bacterial inhibitor against g-type lysozyme

Abstract

Lysozymes are antibacterial effectors of the innate immune system in animals that hydrolyze peptidoglycan. Bacteria have evolved protective mechanisms that contribute to lysozyme tolerance such as the production of lysozyme inhibitors, but only inhibitors of chicken (c-) and invertebrate (i-) type lysozyme have been identified. We here report the discovery… (More)
DOI: 10.1007/s00018-010-0507-3

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