Identification of a Vibrio cholerae chemoreceptor that senses taurine and amino acids as attractants

@article{Nishiyama2016IdentificationOA,
  title={Identification of a Vibrio cholerae chemoreceptor that senses taurine and amino acids as attractants},
  author={Soichiro Nishiyama and Yohei Takahashi and Kentaro Yamamoto and Daisuke Suzuki and Yasuaki Itoh and Kazumasa Sumita and Yumiko Uchida and Michio Homma and Katsumi Imada and Ikuro Kawagishi},
  journal={Scientific Reports},
  year={2016},
  volume={6}
}
Vibrio cholerae, the etiological agent of cholera, was found to be attracted by taurine (2-aminoethanesulfonic acid), a major constituent of human bile. Mlp37, the closest homolog of the previously identified amino acid chemoreceptor Mlp24, was found to mediate taxis to taurine as well as L-serine, L-alanine, L-arginine, and other amino acids. Methylation of Mlp37 was enhanced upon the addition of taurine and amino acids. Isothermal titration calorimetry demonstrated that a purified periplasmic… Expand
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