Identification of a UPC2 homolog in Saccharomyces cerevisiae and its involvement in aerobic sterol uptake.

@article{Shianna2001IdentificationOA,
  title={Identification of a UPC2 homolog in Saccharomyces cerevisiae and its involvement in aerobic sterol uptake.},
  author={Kevin V. Shianna and William Dotson and Shirley Tove and Leo W. Parks},
  journal={Journal of bacteriology},
  year={2001},
  volume={183 3},
  pages={830-4}
}
Saccharomyces cerevisiae normally will not take up sterols from the environment under aerobic conditions. A specific mutant, upc2-1, of the predicted transcriptional activator UPC2 (YDR213w) has been recognized as a strain that allows a high level of aerobic sterol uptake. Another predicted transcriptional activator, the YLR228c gene product, is highly homologous to Upc2p. In fact, at the carboxy terminus 130 of the last 139 amino acids are similar between the two proteins. Since these proteins… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 20 references

A mutation in a purported regulatory gene affects control of sterol uptake in Saccharomyces cerevisiae

  • J. H. Crowley, F. W. Leak, Jr., K. V. Shianna, S. Tove, L. W. Parks
  • J. Bacteriol
  • 1998

Regulation of carbon and phosphate utilization, p. 193–281

  • M. Johnston, M. Carlson
  • Saccharomyces: gene expression,
  • 1992

Similar Papers

Loading similar papers…