Identification of a Chlamydial Protease–Like Activity Factor Responsible for the Degradation of Host Transcription Factors

@article{Zhong2001IdentificationOA,
  title={Identification of a Chlamydial Protease–Like Activity Factor Responsible for the Degradation of Host Transcription Factors},
  author={Guangming Zhong and Peiyi Fan and Hezhao Ji and Feng Dong and Yanqing Huang},
  journal={The Journal of Experimental Medicine},
  year={2001},
  volume={193},
  pages={935 - 942}
}
Microbial pathogens have been selected for the capacity to evade or manipulate host responses in order to survive after infection. Chlamydia, an obligate intracellular pathogen and the causative agent for many human diseases, can escape T lymphocyte immune recognition by degrading host transcription factors required for major histocompatibility complex (MHC… CONTINUE READING