• DOI:10.1172/JCI39933
Corpus ID: 13835837

Identification of a B cell signature associated with renal transplant tolerance in humans.

@article{Newell2010IdentificationOA,
  title={Identification of a B cell signature associated with renal transplant tolerance in humans.},
  author={K. Newell and A. Asare and A. Kirk and Trang D. Gisler and K. Bourcier and M. Suthanthiran and W. Burlingham and W. Marks and I. Sanz and R. Lechler and M. Hernandez-Fuentes and L. Turka and V. Seyfert-Margolis},
  journal={The Journal of clinical investigation},
  year={2010},
  volume={120 6},
  pages={
          1836-47
        }
}

• K. Newell, A. Asare, +10 authors V. Seyfert-Margolis
• Published 2010
• Medicine, Biology
• The Journal of clinical investigation

Establishing long-term allograft acceptance without the requirement for continuous immunosuppression, a condition known as allograft tolerance, is a highly desirable therapeutic goal in solid organ transplantation. Determining which recipients would benefit from withdrawal or minimization of immunosuppression would be greatly facilitated by biomarkers predictive of tolerance. In this study, we identified the largest reported cohort to our knowledge of tolerant renal transplant recipients, as… Expand

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