Identification of TRPC6 as a possible candidate target gene within an amplicon at 11q21-q22.2 for migratory capacity in head and neck squamous cell carcinomas

@article{BernaldodeQuirs2012IdentificationOT,
  title={Identification of TRPC6 as a possible candidate target gene within an amplicon at 11q21-q22.2 for migratory capacity in head and neck squamous cell carcinomas},
  author={Sandra Bernaldo de Quir{\'o}s and Anna Merlo and Pablo Secades and Iriana Zambrano and Ines Saenz de Santa Mar{\'i}a and Nerea Ugidos and Elo{\'i}sa Jantus-Lewintre and Rafael Sirera and Carlos Su{\'a}rez and Mar{\'i}a Dolores Chiara},
  journal={BMC Cancer},
  year={2012},
  volume={13},
  pages={116 - 116}
}
BackgroundCytogenetic and gene expression analyses in head and neck squamous cell carcinomas (HNSCC) have allowed identification of genomic aberrations that may contribute to cancer pathophysiology. Nevertheless, the molecular consequences of numerous genetic alterations still remain unclear.MethodsTo identify novel genes implicated in HNSCC pathogenesis, we analyzed the genomic alterations present in five HNSCC-derived cell lines by array CGH, and compared high level focal gene amplifications… 
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