Identification of TOR Signaling Complexes More TORC for the Cell Growth Engine

  title={Identification of TOR Signaling Complexes More TORC for the Cell Growth Engine},
  author={Robert T. Abraham},
The Target of Rapamycin (TOR) proteins function in signaling pathways that promote protein synthesis and cell growth. In yeast, TOR signaling is regulated by nutrient availability, whereas in metazoan cells TOR activities may be controlled by both nutrients and growth factors. The recent identification of novel TOR-interacting proteins has provided crucial insights into TOR regulation and function. 

From This Paper

Figures, tables, and topics from this paper.
45 Citations
3 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 45 extracted citations


Publications referenced by this paper.
Showing 1-3 of 3 references

roles (if any) between the PI3-kinase-AKT signaling pathway in cell-cycle regulation and DNA damage responses

  • Based on the available evidence, KOG1raptor is pro4, +18 authors R. T. . PI3K-related kinases
  • In Signaling and raptor. However, the notion…
  • 2002

PI 3 Krelated kinases : roles ( if any ) between the PI 3kinaseAKT signaling pathway in cell - cycle regulation and DNA damage responses

  • J. S. Gutkind
  • 2000

Science hints that mTOR may also reside in at least two TORCs

  • R. T. Abraham
  • 1997

Similar Papers

Loading similar papers…