Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target.

@article{Shimokawa2006IdentificationOT,
  title={Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target.},
  author={Takashi Shimokawa and Satoshi Matsushima and Takuya Tsunoda and Hideaki Tahara and Yusuke Nakamura and Yoichi Furukawa},
  journal={International journal of oncology},
  year={2006},
  volume={29 2},
  pages={381-6}
}
In an attempt to isolate potential molecular targets for diagnosis, treatment and/or prevention of colorectal cancer (CRC), we have been analyzing expression profiles of clinical samples from CRC patients using genome-wide cDNA microarray. Among the genes up-regulated frequently in colorectal tumors, we here focused on TOMM34 (34 kDa-translocase of the… CONTINUE READING