Identification of T cell-restricted genes, and signatures for different T cell responses, using a comprehensive collection of microarray datasets.

@article{Chtanova2005IdentificationOT,
  title={Identification of T cell-restricted genes, and signatures for different T cell responses, using a comprehensive collection of microarray datasets.},
  author={Tatyana Chtanova and Rebecca H Newton and Sue Min Liu and Lilach Weininger and Timothy R. Young and Diego G. Silva and Francesco Bertoni and Andrea Rinaldi and Stephane Chappaz and Federica Sallusto and Michael S. Rolph and Charles R Mackay},
  journal={Journal of immunology},
  year={2005},
  volume={175 12},
  pages={7837-47}
}
We used a comprehensive collection of Affymetrix microarray datasets to ascertain which genes or molecules distinguish the known major subsets of human T cells. Our strategy allowed us to identify the genes expressed in most T cell subsets: TCR alphabeta+ and gammadelta+, three effector subsets (Th1, Th2, and T follicular helper cells), T central memory, T effector memory, activated T cells, and others. Our genechip dataset also allowed for identification of genes preferentially or exclusively… CONTINUE READING

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