Identification of T cell lymphoma tumor antigens on human T cell lines.

  title={Identification of T cell lymphoma tumor antigens on human T cell lines.},
  author={Joseph Kaplan and J. Eric Tilton and Ward D. Peterson},
  journal={American journal of hematology},
  volume={1 2},
All human T lymphoblast cell lines have been derived from subjects with leukemia secondary to thymic lymphoblastic lymphoma, a T cell malignancy, suggesting that such lines represent established cultures of neoplastic T cells. Based on this observation, we prepared rabbit antisera to T cell line HSB-2, removed reactivity for histocompatibility antigens and normal T cells by absorption with autocthonous B cell line CCRF-SB and normal thymocytes, and tested the absorbed antisera by complement… CONTINUE READING
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