Identification of T-cell epitopes of SARS-coronavirus for development of peptide-based vaccines and cellular immunity assessment methods.

@article{Chan2011IdentificationOT,
  title={Identification of T-cell epitopes of SARS-coronavirus for development of peptide-based vaccines and cellular immunity assessment methods.},
  author={Paul K S Chan and Selene Ma and Sai Ming Ngai},
  journal={Hong Kong medical journal = Xianggang yi xue za zhi},
  year={2011},
  volume={17 Suppl 6},
  pages={26-30}
}
1. Subjects recovered from SARS-CoV infection retain memory of cellular immune response to epitopes spanning over a few regions of the viral nucleoprotein. Ten such epitopes were identified. 2. The majority of epitopes were predominantly recognised by CD8+ cytotoxic T cells and elicited persistent memory response lasting at least 2 years. 3. There is… CONTINUE READING