Identification of Structural Features of Condensed Tannins That Affect Protein Aggregation

@inproceedings{Ropiak2017IdentificationOS,
  title={Identification of Structural Features of Condensed Tannins That Affect Protein Aggregation},
  author={Honorata M. Ropiak and Peter Lachmann and Aina Ramsay and Rebecca J Green and Irene Mueller-Harvey},
  booktitle={PloS one},
  year={2017}
}
A diverse panel of condensed tannins was used to resolve the confounding effects of size and subunit composition seen previously in tannin-protein interactions. Turbidimetry revealed that size in terms of mean degree of polymerisation (mDP) or average molecular weight (amw) was the most important tannin parameter. The smallest tannin with the relatively largest effect on protein aggregation had an mDP of ~7. The average size was significantly correlated with aggregation of bovine serum albumin… CONTINUE READING