Identification of StARD3 as a lutein-binding protein in the macula of the primate retina.

  title={Identification of StARD3 as a lutein-binding protein in the macula of the primate retina.},
  author={Binxing Li and Preejith P. Vachali and Jeanne M. Frederick and Paul S. Bernstein},
  volume={50 13},
Lutein, zeaxanthin, and their metabolites are the xanthophyll carotenoids that form the macular pigment of the human retina. Epidemiological evidence suggests that high levels of these carotenoids in the diet, serum, and macula are associated with a decreased risk of age-related macular degeneration (AMD), and the AREDS2 study is prospectively testing this hypothesis. Understanding the biochemical mechanisms underlying the selective uptakes of lutein and zeaxanthin into the human macula may… CONTINUE READING
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