Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy

Abstract

Prognosis for patients suffering from malignant glioma has not substantially improved. Specific immunotherapy as a novel treatment concept critically depends on target antigens, which are highly overexpressed in the majority of gliomas, but the number of such antigens is still very limited. SOX2 was identified by screening an expression database for… (More)
DOI: 10.1038/sj.bjc.6603696

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