Identification of SNP markers on 1p36 and association analysis of EPB41 with mandibular prognathism in a Chinese population.

@article{Xue2010IdentificationOS,
  title={Identification of SNP markers on 1p36 and association analysis of EPB41 with mandibular prognathism in a Chinese population.},
  author={Fan Xue and Ricky W. K. Wong and A. Bakr M. Rabie},
  journal={Archives of oral biology},
  year={2010},
  volume={55 11},
  pages={867-72}
}
OBJECTIVE The results of a genome-wide scan suggested that chromosome locus 1p36 might be linked to the etiology of mandibular prognathism (MP) amongst Asian ethnicities. In this study, we performed a two-stage case-control association study to determine whether one or more genes that confer susceptibility to MP are located within this genomic region. DESIGN In the first stage of the study, we examined 103 single nucleotide polymorphisms (SNPs) on 1p36 across an 8.6Mb critical region and… CONTINUE READING
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