Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophils.


BACKGROUND Eosinophils, basophils, and mast cells are believed to be the central tenet cells in allergic conditions including allergic rhinitis, asthma, and eczema. The molecular mechanisms underlying the recruitment of these cells to sites of allergic inflammation are poorly understood. OBJECTIVES Our aim was to identify a common adhesion molecule that… (More)


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