Identification of RASSF8 as a candidate lung tumor suppressor gene

@article{Falvella2006IdentificationOR,
  title={Identification of RASSF8 as a candidate lung tumor suppressor gene},
  author={Felicia Stefania Falvella and Giacomo Manenti and Monica Spinola and Carmen Pignatiello and Barbara Conti and Ugo Pastorino and Tommaso A Dragani},
  journal={Oncogene},
  year={2006},
  volume={25},
  pages={3934-3938}
}
The RASSF8 gene, which maps close to the KRAS2 gene, contains a RAS-associated domain and encodes a protein that is evolutionarily conserved from fish to humans. Analysis of the RASSF8 transcript revealed a complex expression pattern of 5′-UTR mRNA isoforms in normal lung and in lung adenocarcinomas (ADCAs), with no apparent differences. However, RASSF8… CONTINUE READING