Identification of Protein Partners in Mycobacteria Using a Single-Step Affinity Purification Method

@inproceedings{Pociski2014IdentificationOP,
  title={Identification of Protein Partners in Mycobacteria Using a Single-Step Affinity Purification Method},
  author={Przemysław Płociński and Daniel Laubitz and Dominik Cysewski and Krystian Stoduś and Katarzyna Cholewa Kowalska and Andrzej Dziembowski},
  booktitle={PloS one},
  year={2014}
}
Tuberculosis is a leading cause of death in developing countries. Efforts are being made to both prevent its spread and improve curability rates. Understanding the biology of the bacteria causing the disease, Mycobacterium tuberculosis (M. tuberculosis), is thus vital. We have implemented improved screening methods for protein-protein interactions based on affinity purification followed by high-resolution mass spectrometry. This method can be efficiently applied to both medium- and high… CONTINUE READING

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