Identification of Phosphorylation Sites Regulating sst3 Somatostatin Receptor Trafficking.

@article{Lehmann2016IdentificationOP,
  title={Identification of Phosphorylation Sites Regulating sst3 Somatostatin Receptor Trafficking.},
  author={Andreas Lehmann and Andrea rer. nat. Kliewer and Thomas G{\"u}nther and Falko rer. nat. Nagel and Stefan Schulz},
  journal={Molecular endocrinology},
  year={2016},
  volume={30 6},
  pages={
          645-59
        }
}
The human somatostatin receptor 3 (sst3) is expressed in about 50% of all neuroendocrine tumors and hence a promising target for multireceptor somatostatin analogs. The sst3 receptor is unique among ssts in that it exhibits a very long intracellular C-terminal tail containing a huge number of potential phosphate acceptor sites. Consequently, our knowledge about the functional role of the C-terminal tail in sst3 receptor regulation is very limited. Here, we have generated a series of… CONTINUE READING
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