Identification of Patients With Documented Pathologic Complete Response in the Breast After Neoadjuvant Chemotherapy for Omission of Axillary Surgery.

@article{Tadros2017IdentificationOP,
  title={Identification of Patients With Documented Pathologic Complete Response in the Breast After Neoadjuvant Chemotherapy for Omission of Axillary Surgery.},
  author={Audree B Tadros and Wei Yang and Savitri Krishnamurthy and Gaiane Margishvili Rauch and Benjamin D. Smith and Vicente Valero and Dalliah MaShon Black and Anthony J. Lucci and Abigail Suzanne Caudle and Sarah Marie DeSnyder and Mediget Teshome and Carlos Hernando Barcenas and Makesha V Miggins and Beatriz E. Adrada and Tanya W Moseley and Rosa Frances Hwang and Kelly K. Hunt and Henry Mark Kuerer},
  journal={JAMA surgery},
  year={2017},
  volume={152 7},
  pages={
          665-670
        }
}
Importance A pathologic complete response (pCR; no invasive or in situ cancer) occurs in 40% to 50% of patients with HER2-positive (HER2+) and triple-negative (TN) breast cancer. The need for surgery if percutaneous biopsy of the breast after neoadjuvant chemotherapy (NCT) indicates pCR in the breast (hereinafter referred to as breast pCR) has been questioned, and appropriate management of the axilla in such patients is unknown. Objective To identify patients among exceptional responders to… CONTINUE READING
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