Identification of PLTP as an LXR target gene and apoE as an FXR target gene reveals overlapping targets for the two nuclear receptors.

@article{Mak2002IdentificationOP,
  title={Identification of PLTP as an LXR target gene and apoE as an FXR target gene reveals overlapping targets for the two nuclear receptors.},
  author={Puiying A. Mak and Heidi R. Kast-Woelbern and Andrew M Anisfeld and Peter A. Edwards},
  journal={Journal of lipid research},
  year={2002},
  volume={43 12},
  pages={2037-41}
}
Affymetrix microarray data and Northern blot assays demonstrated that phospholipid transfer protein (PLTP) was induced 6-fold when either murine or human macrophages were incubated in the presence of ligands for the liver X receptor (LXR) and the retinoid X receptor. Two functional LXR response elements (LXREs) were identified and characterized in the… CONTINUE READING