Identification of PDGF-BB binding to thymosin β4 by chemical cross-linking.

Abstract

INTRODUCTION The purpose of our work was to identify unknown interaction partners of thymosin β4 (Tβ4). It was suggested that Tβ4 could be an antifibrotic drug for treatment of liver fibrogenesis, because Tβ4 prevents the platelet-derived growth factor-BB (PDGF-BB)-induced activation of hepatic stellate cells (HSCs). Very little information is available how… (More)
DOI: 10.1517/14712598.2015.1014793

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