Identification of Oropouche Orthobunyavirus in the cerebrospinal fluid of three patients in the Amazonas, Brazil.

@article{Bastos2012IdentificationOO,
  title={Identification of Oropouche Orthobunyavirus in the cerebrospinal fluid of three patients in the Amazonas, Brazil.},
  author={Michele de Souza Bastos and Luiz Tadeu Moraes Figueiredo and Felipe Gomes Naveca and Rossicl{\'e}ia Lins Monte and Nat{\'a}lia Lessa and Regina Maria Pinto de Figueiredo and Jo{\~a}o Bosco de Lima Gimaque and Guilherme Pivoto Jo{\~a}o and Rajendranath Ramasawmy and Maria Paula Gomes Mour{\~a}o},
  journal={The American journal of tropical medicine and hygiene},
  year={2012},
  volume={86 4},
  pages={732-5}
}
Oropouche fever is the second most frequent arboviral infection in Brazil, surpassed only by dengue. Oropouche virus (OROV) causes large and explosive outbreaks of acute febrile illness in cities and villages in the Amazon and Central-Plateau regions. Cerebrospinal fluid (CSF) samples from 110 meningoencephalitis patients were analyzed. The RNA extracted from fluid was submitted to reverse transcription-polymerase chain reaction and sequencing to identify OROV. Three CSF samples showed the… CONTINUE READING

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