Identification of Novel Regulatory Cholesterol Metabolite, 5-Cholesten, 3Î2,25-Diol, Disulfate


Oxysterol sulfation plays an important role in regulation of lipid metabolism and inflammatory responses. In the present study, we report the discovery of a novel regulatory sulfated oxysterol in nuclei of primary rat hepatocytes after overexpression of the gene encoding mitochondrial cholesterol delivery protein (StarD1). Forty-eight hours after infection… (More)


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