Identification of Novel Changes in Human Skeletal Muscle Proteome After Roux-en-Y Gastric Bypass Surgery

@inproceedings{Campbell2016IdentificationON,
  title={Identification of Novel Changes in Human Skeletal Muscle Proteome After Roux-en-Y Gastric Bypass Surgery},
  author={Latoya E. Campbell and Paul R. Langlais and Samantha E. Day and Richard L. Coletta and Tonya R. Benjamin and Elena De Filippis and James A. Madura and Lawrence J. Mandarino and Lori R. Roust and Dawn K. Coletta},
  booktitle={Diabetes},
  year={2016}
}
The mechanisms of metabolic improvements after Roux-en-Y gastric bypass (RYGB) surgery are not entirely clear. Therefore, the aim of our study was to investigate the role of obesity and RYGB on the human skeletal muscle proteome. Basal muscle biopsies were obtained from seven obese (BMI >40 kg/m(2)) female subjects (45.1 ± 3.6 years) pre- and 3 months post-RYGB, and euglycemic-hyperinsulinemic clamps were used to assess insulin sensitivity. Four age-matched (48.5 ± 4.7 years) lean (BMI <25 kg/m… CONTINUE READING
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References

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Enhanced insulin signaling in human skeletal muscle and adipose tissue following gastric bypass surgery.

American journal of physiology. Regulatory, integrative and comparative physiology • 2015
View 2 Excerpts

Reduction in in fl ammatory gene expression in skeletal muscle from Roux - enY gastric bypass patients randomized to omentectomy

RA Tamboli, T Hajri, A Jiang
PLoS One • 2011

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