Identification of New Genes Contributing to the Extreme Radioresistance of Deinococcus radiodurans Using a Tn5-Based Transposon Mutant Library

@article{Dulermo2015IdentificationON,
  title={Identification of New Genes Contributing to the Extreme Radioresistance of Deinococcus radiodurans Using a Tn5-Based Transposon Mutant Library},
  author={R. Dulermo and T. Onodera and G. Coste and Fanny M. Passot and M. Dutertre and Martine Porteron and F. Confalonieri and S. Sommer and C. Pasternak},
  journal={PLoS ONE},
  year={2015},
  volume={10}
}
Here, we have developed an extremely efficient in vivo Tn5-based mutagenesis procedure to construct a Deinococcus radiodurans insertion mutant library subsequently screened for sensitivity to genotoxic agents such as γ and UV radiations or mitomycin C. The genes inactivated in radiosensitive mutants belong to various functional categories, including DNA repair functions, stress responses, signal transduction, membrane transport, several metabolic pathways, and genes of unknown function… Expand
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References

SHOWING 1-10 OF 100 REFERENCES
DrRRA: a novel response regulator essential for the extreme radioresistance of Deinococcus radiodurans
  • 71
PprI: a general switch responsible for extreme radioresistance of Deinococcus radiodurans.
  • 152
Genome of the Extremely Radiation-Resistant Bacterium Deinococcus radiodurans Viewed from the Perspective of Comparative Genomics
  • 621
  • PDF
...
1
2
3
4
5
...