Identification of Mycoplasma incognitus infection in patients with AIDS: an immunohistochemical, in situ hybridization and ultrastructural study.

@article{Lo1989IdentificationOM,
  title={Identification of Mycoplasma incognitus infection in patients with AIDS: an immunohistochemical, in situ hybridization and ultrastructural study.},
  author={S. C. Lo and Matthew S Dawson and Diana M. L. Wong and P. W. Newton and Masahiro Sonoda and Walter F. Engler and Richard Y-H Wang and Jim W-K Shih and Harvey J. Alter and Douglas J. Wear},
  journal={The American journal of tropical medicine and hygiene},
  year={1989},
  volume={41 5},
  pages={601-16}
}
Monoclonal antibodies (Mabs) were developed against antigens from a pure culture of Mycoplasma incognitus grown in modified SP-4 medium. All the Mabs obtained were shown to react only with M. incognitus, and not with other species of human mycoplasma. The Mabs identified M. incognitus immunohistologically in thymus, liver, spleen, lymph node, or brain from 22 patients with AIDS, as well as in 2 placentas delivered by patients with AIDS. Using an 35S-labeled DNA probe specific for M. incognitus… CONTINUE READING